| Guinness Premiership |
| Sat 05 Sept 2009 | Saracens - London Irish | 18-14 (B) |
|
| Sun 13 Sept 2009 | London Irish - Gloucester | (B) 40-10 |
|
| Sun 20 Sept 2009 | Leeds - London Irish | 7-56 (B) |
|
| Sun 27 Sept 2009 | London Irish - Wasps | 28-16 |
|
| Fri 02 Oct 2009 | Sale - London Irish | 8-11 |
|
| Sat 24 Oct 2009 | London Irish - Leicester | 18-12 |
|
| Sat 31 Oct 2009 | Harlequins - London Irish | 9-9 |
|
| Sun 22 Nov 2009 | London Irish - Newcastle | (B) 11-15 |
|
| Sat 28 Nov 2009 | Bath - London Irish | 0-16 |
|
| Sat 05 Dec 2009 | London Irish - Worcester | 16-16 |
|
| Sun 27 Dec 2009 | London Irish - Saracens | 23-19 |
|
| Sat 02 Jan 2010 | Northampton - London Irish | 24-22 (B) |
|
| Sun 14 Feb 2010 | London Irish - Bath | 22-35 |
|
| Sat 20 Feb 2010 | Newcastle - London Irish | 12-12 |
|
| Sun 28 Feb 2010 | London Irish - Harlequins | 29-14 |
|
| Sat 06 Mar 2010 | Leicester - London Irish | 35-19 |
|
| Sun 28 Mar 2010 | London Irish - Sale | |
|
| Sun 04 Apr 2010 | Wasps - London Irish | |
|
| Sat 10 Apr 2010 | Worcester - London Irish | |
|
| Sun 18 Apr 2010 | London Irish - Leeds | |
|
| Sat 24 Apr 2010 | Gloucester - London Irish | |
|
| Sat 08 May 2010 | London Irish - Northampton | |
|
